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Artegiani Group

Lucia Bracesco

Group: Artegiani Group

About Lucia 

I am a molecular biologist from Italy, driven by a deep-rooted curiosity towards the mechanisms of life. I started my academic journey at the University of Padova, Italy, where I studied Molecular Biology, and then mastered in Paris, France, at the European Master of Genetics. During my time in Paris, I worked on leukemia at the Gustave Roussy Institute, fostering my interest in the
field of cancer biology and motivating me to continue working in this field for my PhD.

My Project: Elucidating the role of BAP1 in fibrolamellar carcinoma

Fibrolamellar Carcinoma (FLC) is a rare but deadly liver cancer mostly occurring in children or young adults, with limited treatment options. Our aim is to improve the molecular understanding of this disease. Recently, BAP1 mutations have been associated with this cancer type but their contribution to tumorigenesis is still unclear. To further investigate this mechanism, I will use state-of-the-art organoid cultures. These techniques will help us to study how BAP1 mutations can influence cell identity in different liver cell types and how this is linked to cancer development.